Technology

Autodisplay Biotech is active in the field of autodisplay technology. This technology enables the display of proteins on the surface of Escherichia coli (E. coli). Advantages are that the proteins on the surface are immobilised and stabilised, fully accessible and the dimerisation/aggregation of multi protein complexes is possible.

Furthermore, the purification is very easy, the DNA is an internal label and there is self replication. As each E. coli could have a different protein on its surface, the specific binding of corresponding external proteins is possible. The target structures can be selected from the mixture by efficient analytical methods like fluorescence activated cell sorting (FACS).

Autodisplay technology enables interesting applications and Autodisplay Biotech has identified possibilities in the field of biocatalysis, drug discovery, bioanalytics (biochips, ELISA) and antibody development (small protein drugs). For example, the proteins on the surface can be used as efficient biocatalysts for the synthesis of steroids and rare sugars.